The impact of hyperoxemia on mortality and neurological outcomes in traumatic brain injury: a systematic review and meta-analysis

Key Points

• The aim is to assess the effects of hyperoxemia on outcomes and mortality in traumatic brain injury patients.
• Conducted a systematic review and meta-analysis of existing studies
• Analyzed the relationship between hyperoxemia and neurological outcomes
• Evaluated mortality rates associated with oxygen therapy
• Insufficient evidence found to discourage the use of moderate hyperoxemia in TBI patients
• Exploratory analyses hint at potential benefits from early moderate hyperoxemia
• Highlights the need for future high-quality prospective studies