What question did this study set out to answer?

To report the first autochthonous cases of monkeypox virus clade Ib in the Netherlands and analyze their transmission.

January 25, 2026Eurosurveillance0 citationsOpen Access

First detection and autochthonous transmission of monkeypox virus clade Ib in the Netherlands, October to November, 2025

JEJelte Elsinga CVCeline A. van de Ven AVAnne de Vries

Key Points

To report the first autochthonous cases of monkeypox virus clade Ib in the Netherlands and analyze their transmission.
Identified eight cases of monkeypox virus infection.
Performed phylogenetic analysis to trace virus origins.
Conducted contact tracing to assess transmission routes.
Eight autochthonous cases reported, all in men aged 25–65.
No hospital admissions or antiviral treatments were required.
Evidence of multiple introductions and cryptic circulation within the community.

Abstract

In October–November 2025, eight autochthonous cases of monkeypox (MPXV) clade Ib virus infection were reported in the Netherlands. All cases were men who have sex with men aged 25–65; none required hospital admission or antiviral treatment. Phylogenetic analysis combined with contact tracing suggest multiple introductions or cryptic circulation with onwards transmission within the community. Highly related international sequences were identified dating back to August 2025, indicating sustained global community transmission of clade Ib outside the African continent.

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Cite This Study

Elsinga et al. (Thu,) studied this question.

synapsesocial.com/papers/6975b28afeba4585c2d6e0b6 https://doi.org/https://doi.org/10.2807/1560-7917.es.2026.31.3.2500958

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