Omental wrapping of the pancreaticojejunostomy during pancreatoduodenectomy to prevent clinically relevant POPF: a GRADE-assessed systematic review and meta-analysis featuring geographic subgroup analysis.

Key Points

• This research aims to explore the effectiveness of omental wrapping of pancreaticojejunostomy to reduce post-operative pancreatic fistulas.
• Conducted a systematic review and meta-analysis
• Included geographic subgroup analysis
• Assessed studies using GRADE methodology
• Omental wrapping significantly reduces the incidence of clinically relevant POPF
• Improves perioperative recovery without increasing surgery duration
• Support for selective adoption in high-risk anatomical contexts