Stool DNA-based SDC2 Methylation Test for the Screening of Colorectal Neoplasia in an Asymptomatic, Average-Risk Population

Key Points

• The aim is to evaluate the effectiveness of a stool DNA-based SDC2 methylation test for colorectal neoplasia screening in average-risk individuals.
• Utilized a stool DNA-based SDC2 methylation test in a clinical setting.
• Targeted average-risk individuals for colorectal cancer (CRC).
• Assessed positive predictive value for any colorectal neoplasia (CRN).
• The stool DNA test demonstrated a high positive predictive value for detecting colorectal neoplasia.
• Results indicate the test's potential effectiveness in real-world screening programs.