The prognostic value of miR-323b-5p in non-small cell lung cancer and its mechanism of targeting IL1A in regulating the proliferation and cell cycle of non-small cell lung cancer cells | Synapse
January 25, 2026Open Access
The prognostic value of miR-323b-5p in non-small cell lung cancer and its mechanism of targeting IL1A in regulating the proliferation and cell cycle of non-small cell lung cancer cells
Key Points
To investigate the prognostic role of miR-323b-5p in non-small cell lung cancer (NSCLC) and its mechanism in regulating IL1A.
Analyzed miR-323b-5p levels in NSCLC samples
Examined the role of miR-323b-5p in regulating IL1A
Studied the impact on cell proliferation and cell cycle progression
Low miR-323b-5p levels correlate with poor prognosis in NSCLC
miR-323b-5p targets IL1A to moderate the cell cycle
Inhibition of IL1A leads to reduced cell proliferation in NSCLC cells
Abstract
Low levels of miR-323b-5p predict a poor prognosis for NSCLC. miR-323b-5p regulates the cell cycle of NSCLC cells by targeting IL1A, thereby inhibiting cell proliferation.