Lacrimal gland duct obstruction and dacryops: Unravelling its pathogenesis with proteomics and cellular profiling

Key Points

• The research aims to uncover the underlying mechanisms of lacrimal gland duct obstruction and dacryops through advanced analysis techniques.
• Analysis of cyst fluid composition and inflammatory responses
• Profiling of matrix metalloproteinases (MMPs) and apolipoproteins
• Evaluation of fibrosis and neural network alterations
• Dacryops shows increased MMP levels and inflammation
• Cyst fluid is abundant in apolipoproteins and immunoglobulins
• Observation of fibrosis and disruption of the periductal neural network