Characterisation of the Novel HLA‐C*07:1226 Allele by Next Generation Sequencing

Key Points

• The study aims to characterize the novel HLA-C*07:1226 allele to understand its unique genetic features.
• Utilized next generation sequencing for allele analysis
• Focused on nucleotide variations at specific positions
• Examined the differences between HLA-C*07:1226 and HLA-C*07:01:01:01
• Identified a non-synonymous nucleotide change at position 2278
• Confirmed the genetic distinctiveness of the HLA-C*07:1226 allele