This review highlights recent advancements (2021–2025) in the synthesis of 4‐(indol‐3‐yl)‐4 H ‐chromene derivatives, a promising class of compounds with diverse biological activities, including anticancer, antifungal, antitumor, anti‐HIV, and antioxidant properties. The focus is on multicomponent reactions (MCRs) as a valuable tool for efficient synthesis, offering benefits such as environmental sustainability and precise targeting. The review explores MCR strategies and substrate scope, shedding light on their potential therapeutic applications.
Diana et al. (Wed,) studied this question.