Zn(II) coordinated organic small molecules as chiral fluorescent probe for discrimination and detection of tyrosine enantiomers

Key Points

• To design chiral organic small molecules that can selectively detect and discriminate between tyrosine enantiomers.
• Synthesis of clamp-shaped chiral organic small molecules using amidation reactions.
• Linking (1R,2R)-(+)-1,2-diphenyl-1,2-ethylenediamine with 5-methylsalicylic acid.
• Characterization of probe efficacy in detecting tyrosine enantiomers.
• Successfully synthesized the chiral organic small molecules with high selectivity for tyrosine enantiomers.
• Demonstrated the ability of the probes to differentiate between tyrosine enantiomers effectively.
• Fluorescent signal variations correlated with the presence of different tyrosine enantiomers.