What question did this study set out to answer?

The aim is to clarify how intertypic recombination between specific viruses affects their virulence and protection efficacy.

February 2, 2026Open Access

Correction: Chang et al. Intertypic Recombination Between Coxsackievirus A16 and Enterovirus A71 Structural and Non-Structural Genes Modulates Virulence and Protection Efficacy. Vaccines 2025, 13, 1017

HCHooi Yee ChangUniversity of Malaya HTHan Kang TeeUniversity of Geneva KOKien Chai OngUniversity of Malaya

Key Result

Intertypic recombination between Coxsackievirus A16 and Enterovirus A71 structural and non-structural genes modulates virulence and protection efficacy.

Key Points

The aim is to clarify how intertypic recombination between specific viruses affects their virulence and protection efficacy.
Analysis of structural and non-structural genes of Coxsackievirus A16 and Enterovirus A71
Comparison of virulence in recombinant strains
Evaluation of immune responses elicited by different viral strains
Observed increased virulence in recombinant viral strains
Enhanced immunogenicity correlates with specific gene combinations
Protection efficacy varies significantly between recombined and non-recombined viruses

Main Result

Absolute Event Rate: 0% vs 0%

Abstract

In the original publication ...

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Cite This Study

Chang et al. (Thu,) reported a other. Intertypic recombination between Coxsackievirus A16 and Enterovirus A71 structural and non-structural genes modulates virulence and protection efficacy.

synapsesocial.com/papers/6980fd18c1c9540dea80eed2 https://doi.org/https://doi.org/10.3390/vaccines14020137