The aim is to explore how extracellular cGMP levels relate to the response of C4-1 cervical cancer cells to ionizing radiation.
Monitored extracellular cGMP levels in C4-1 cervical cancer cells.
Assessed cellular response to ionizing radiation exposure.
Evaluated potential of cGMP as a biomarker for radiation therapy.
Higher extracellular cGMP levels correlate with better response to radiation therapy.
cGMP levels may help tailor radiation treatment for improved outcomes.
Abstract
From a translational perspective, extracellular cGMP levels may be used to monitor effects and be a potential tool for individualization of radiation therapy (RT).