N-Arylation of Isatins with Diaryliodonium Salts under Transition Metal-Free Conditions

Key Points

• The research aims to develop a transition metal-free method for the N-arylation of isatins using diaryliodonium salts.
• Utilized diaryliodonium salts as reagents for N-arylation
• Performed reactions under transition metal-free conditions
• Examined the biological activity of substituted isatins
• Successfully synthesized various substituted isatins
• Demonstrated versatility in accessing medicine-relevant compounds
• Highlighted the potential biological activities of new derivatives