What question did this study set out to answer?

To investigate the relationship between PD-L1 expression status and tumor location in patients with non-small cell lung cancer.

February 2, 2026

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Tumor Location Significantly Correlates With PD-L1 Status in Patients With Small Sized Non-small Cell Lung Cancer

TTTakuma TsukiokaOsaka City General Hospital RNRyu NakajimaOsaka City General Hospital KCKyukwang ChungOsaka City General Hospital

Key Points

To investigate the relationship between PD-L1 expression status and tumor location in patients with non-small cell lung cancer.
Analyzed tumor samples for PD-L1 expression status
Evaluated histological types and tumor location
Used correlation metrics to assess relationships
Observed a significant correlation between PD-L1 status and tumor location
Differences in the cancer microenvironment were noted as potential influencing factors

Abstract

PD-L1 expression status significantly correlated with CTR, histological type and tumor location. This is the first report demonstrating a significant correlation between PD-L1 expression and tumor location in NSCLC. We believe that differences in the cancer microenvironment based on tumor location influence PD-L1 expression status in cancer cells.

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Tumor Location Significantly Correlates With PD-L1 Status in Patients With Small Sized Non-small Cell Lung Cancer

Key Points

Abstract

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