Kidney function and five types of psychiatric traits/disorders: a bidirectional mendelian randomisation study

Key Points

• The study aims to investigate the causal relationship between psychiatric disorders and kidney function.
• Conducted a bidirectional mendelian randomisation analysis
• Examined multiple psychiatric traits and kidney function traits
• Assessed the strength of causal relationships between the two domains.
• Marked bidirectional genetic causality between psychiatric disorders and kidney function observed
• More pronounced causal effects from psychiatric traits/disorders on kidney impairment detected
• Identified modifiable lifestyle factors as targets for prevention and intervention.