Circulating cell-free DNA as a biomarker for immune function and disease progression in HIV-infected patients: a cross-sectional observational study

Key Points

• This study aims to explore the relationship between circulating cell-free DNA levels and immune function in HIV-infected individuals.
• Conducted a cross-sectional observational study of HIV-infected patients.
• Measured circulating cell-free DNA (ccfDNA) levels in participants.
• Evaluated the correlation between ccfDNA levels and indicators of immune function.
• ccfDNA levels were found to be closely linked to immune dysfunction.
• Higher ccfDNA levels may indicate poorer immune status.
• ccfDNA shows potential as a complementary biomarker for monitoring immune health in HIV patients.