Water-soluble tomato concentrate alleviates neuron apoptosis though activating ERK/CREB/BDNF signaling pathway in ischemic stroke

Key Points

• The research aims to investigate how water-soluble tomato concentrate influences neuron apoptosis and the associated signaling pathways in ischemic stroke.
• Utilized water-soluble tomato concentrate as an intervention
• Examined effects on neuron apoptosis
• Analyzed activation of ERK/CREB/BDNF signaling pathway
• Conducted experiments in a controlled setting
• Water-soluble tomato concentrate significantly reduces neuron apoptosis
• Activation of the ERK/CREB/BDNF pathway is observed
• Neuroprotective effects are established in ischemic conditions