What question did this study set out to answer?

The central aim is to compile and analyze single-herb therapies for managing diabetes (Prameha) in Ayurveda.

February 6, 2026Open Access

Ekamoolika Prayoga in Prameha: A Compilation of Classical Review

Key Points

The central aim is to compile and analyze single-herb therapies for managing diabetes (Prameha) in Ayurveda.
Compilation of Ekamoolika Prayogas from classical Ayurvedic texts like Brihattrayee.
Analysis of the Rasapanchaka properties of these herbs.
Review of pharmacological activities related to diabetes management.
Identified numerous effective single-herb therapies for diabetes.
Herbs exhibit properties that balance the body's doshas and manage symptoms.
Demonstrated pharmacological activities including hypoglycaemic and insulin-sensitizing effects.

Abstract

Ayurveda, one of the most ancient and well-documented systems of medicine, describes Diabetes Mellitus under the term Prameha or Madhumeha. The condition arises from indulgence in causative factors leading to vitiation of Kapha and Meda, which descend through the Mutravaha Srotas and localize at the Bastimukha, producing symptoms such as Prabhoota Mutrata and Kharapada Daha etc. Numerous Ekamoolika Prayogas (single-herb therapy) are mentioned in classical Ayurvedic treatises for various diseases, including Prameha. This review compiles Ekamoolika Prayogas for Prameha from the Brihattrayee and analyses the Rasapanchaka of the mentioned herbs. Ekamoolika Prayoga offers a simple, economical, and effective therapeutic approach. Most herbs described possess Tikta-Katu-Kashaya Rasa, Laghu-Ruksha Guna, Ushna Virya, and Katu Vipaka, indicating Tridoshahara and Medohara properties. Pharmacologically, these herbs exhibit hypoglycaemic, antioxidant, and insulin-sensitizing activities, supporting their efficacy in managing Prameha.

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