Acute Glomerulonephritis Complicating Pulmonary Tuberculosis

Acute glomerulonephritis associated with tuberculosis is a rare but serious complication, most often resulting from immunological mechanisms triggered by Mycobacterium tuberculosis infection. Clinical presentations are heterogeneous, ranging from isolated proteinuria to rapidly progressive acute renal failure, with various histological patterns reported. We report the case of acute glomerulonephritis occurring in the aftermath of pulmonary tuberculosis in a 47-year-old patient, a chronic active smoker, revealed by the sudden onset of acute nephrotic syndrome associated with deterioration of general condition. Biological investigations showed a rapid decline in glomerular filtration rate, and the diagnosis was confirmed by renal biopsy.