Pivotal role of interleukin 27 serum level and missense variant (rs181206) in multiple sclerosis

Key Points

• The study aims to examine the role of interleukin 27 and its genetic variations in the development of multiple sclerosis.
• Assessment of interleukin 27 serum levels in relation to MS susceptibility.
• Analysis of the missense variant (rs181206) in the context of genetic risk factors.
• TT genotype and T allele increase the risk of developing multiple sclerosis.
• C allele is associated with a lower risk of developing multiple sclerosis.