Three-Component Synthesis and Antibacterial Activity of 5-Aryl-4-acyl-3-hydroxy-1-(4-methoxyphenyl)-3-pyrroline-2-ones

Key Points

• The aim is to synthesize new pyrroline-2-ones and evaluate their antibacterial properties.
• Synthesis of compounds through the reaction of methyl esters with aromatic aldehyde and p-anisidine.
• In vitro testing against Staphylococcus aureus and Escherichia coli strains.
• Several new compounds were successfully synthesized.
• The antibacterial activity showed effectiveness against both tested bacterial strains.

Abstract