Time-Dependent Neurovascular Unit Dysfunction in Ischemic Stroke: Mechanisms of Neurovascular Uncoupling and its Clinical Impact

Key Points

• The study aims to explore the mechanisms of neurovascular unit dysfunction and its clinical implications following ischemic stroke.
• Investigated the role of neurovascular unit in stroke injury and recovery.
• Analyzed phase-specific therapeutic strategies.
• Focused on targeting inflammation, oxidative stress, and blood-brain barrier instability.
• Identified neurovascular uncoupling as a critical factor in stroke outcomes.
• Demonstrated that biomarkers can guide personalized stroke management strategies.
• Highlighted the importance of addressing both acute injury and chronic recovery.