The review provides information of the development and testing of biologically active surgical suture material at laboratory and clinical conditions. Filaments with antimicrobial effect take the first place among all developments of active pharmaceutical ingredients for prevent infection in the surgical area. It also describes the development of suture material with anti-inflammatory, analgesic and regenerative effects. The article describes the experience of using suture material with stem cells to stimulate angiogenesis and remodel damaged tissues. Modern technologies make it possible to produce new suture filaments with various drugs, with different functionality, biodegradability and biological properties compared to intact commercial filaments.
A.G. Malanyeva (Wed,) studied this question.