Overweight and obesity significantly increased the risk of metabolic syndrome (OR 21.76 and 50.32 respectively) and hyperuricaemia (OR 3.69 and 1.75 respectively) among children and adolescents aged 6-17 in Western China, with a hyperuricaemia prevalence of 27.6%.
Cross-Sectional (n=2,423)
Yes
This study highlights a complex double burden of malnutrition among children and adolescents in western China, characterized by high rates of hyperuricemia, vitamin D inadequacy, and zinc deficiency alongside traditional undernutrition.
Effect estimate: OR 3.69 for hyperuricaemia in overweight vs normal weight; OR 21.76 for metabolic syndrome in overweight vs normal weight; OR 50.32 for metabolic syndrome in obesity vs normal weight; PR 2.04 for overnutrition-related disorders in overweight; PR 3.47 in obesity (95% CI MetS vs overweight 10.29-46.03; MetS vs obesity 23.08-109.74; Hyperuricaemia vs overweight 2.40-5.66; Hyperuricaemia vs obesity 1.25-2.45)
p-value: p=<0.001 for key comparisons
Abstract Nutrition is crucial for the growth of children and adolescents. This study investigated multiple nutritional problems and influencing factors among 2,423 students aged 6-17 in Guizhou Province, using questionnaire surveys, physical examinations, and blood tests. Multifactorial logistic and Poisson regression analyses were used to identify determinants of overnutrition and undernutrition. The results showed a distinct profile compared to national averages: wasting was more prevalent (9.6%), while overweight (8.6%) and obesity (5.0%) were less common. Notably, hyperuricemia (27.6%) and zinc deficiency (17.9%) were elevated, whereas classical metabolic syndrome (2.3%) was lower, delineating a regional pattern that prioritizes these emerging and micronutrient issues. Marginal vitamin A deficiency (17.2%) and vitamin D inadequacy (50.9%) remained significant. Older age (11-17 years) was a strong risk factor for overnutrition-related disorders and hyperuricemia (All p <0.001). Overweight/obesity increased risks of hyperuricemia and metabolic syndrome (All p <0.001). Being female was a major risk factor for undernutrition (PR=1.27, 95%CI: 1.19-1.35, p <0.001) and vitamin D deficiency (AOR=2.51, 95%CI: 2.10-3.00, p <0.001), but a protective factor against hyperuricemia (AOR=0.34, 95%CI: 0.27-0.41, p <0.001). Frequent sugary drink consumption (≥3/week) elevated hyperuricemia risk (AOR=1.33, 95%CI: 1.05-1.69, p =0.020). This study underscores a complex double burden of malnutrition in western China, characterized by specific priority areas, and necessitates tailored, multi-component interventions such as limiting sugary drinks and focusing nutrition support on adolescent girls.
Sun et al. (Fri,) conducted a cross-sectional in Children and adolescents aged 6-17 years in Guizhou Province, Western China with assessment of multiple nutritional disorders including overnutrition and undernutrition (n=2,423). Overweight and obesity significantly increased the risk of metabolic syndrome (OR 21.76 and 50.32 respectively) and hyperuricaemia (OR 3.69 and 1.75 respectively) among children and adolescents aged 6-17 in Western China, with a hyperuricaemia prevalence of 27.6%.