In pulmonary hypertension, 3D RVOT ejection fraction was 30.4% vs 44.2% in controls and <30.4% predicted higher risk and worse clinical outcomes.
Does 3D echocardiographic assessment of RVOT-EF correlate with disease severity and predict clinical worsening in patients with pulmonary hypertension?
Segmental 3D echocardiographic analysis of RVOT-EF identifies high-risk pulmonary hypertension patients who may experience clinical worsening despite having normal overall right ventricular function.
Absolute Event Rate: 0% vs 0%
Right ventricular outflow tract (RVOT) function is not systematically quantified by three-dimensional (3D) echocardiography. We tested the hypothesis that loss of RVOT function in pulmonary hypertension (PH) is related to disease severity independently of other echocardiographic parameters. In this observational study, patients with PH, disease controls, and a matched healthy control group underwent 3D echocardiography and RVOT analysis using ReVISION software. The study included 43 patients (38 with PH, 5 disease controls) and 43 healthy controls. Median 3D RVOT-ejection fraction (EF) was 30.4% in the patients and 44.2% in the healthy controls (p < 0.001). Patients with low 3D RVOT-EF (<30.4%) were more frequently categorized in higher-risk groups and had a higher incidence of clinical worsening than those with high 3D RVOT-EF. Even in patients with RV-EF ≥35%, those with low 3D RVOT-EF had worse outcomes. Segmental RVOT analysis identifies high-risk patients even with normal overall RV function.
Rocha et al. (Wed,) reported a other. In pulmonary hypertension, 3D RVOT ejection fraction was 30.4% vs 44.2% in controls and <30.4% predicted higher risk and worse clinical outcomes.