Catalytic Asymmetric Construction of Medium-Sized Ring Systems with Single Axial or Inherent Chiral Element

Key Points

• The central aim is to review the synthesis of medium-sized cyclic compounds with single axial or inherent chirality.
• Review of existing literature on synthetic methodologies
• Analysis of recent advancements in medium-sized cyclic compound synthesis
• Discussion of applications in medicinal chemistry and materials science
• Highlighting the unique properties of inherently and axially chiral compounds
• Summarizing representative advances in synthesis techniques
• Indicating their implications in various domains such as medicinal chemistry and asymmetric catalysis