What does this research mean for the field?

Transcatheter tricuspid valve annuloplasty achieved TR grade ≤2 at discharge in 70% of patients, with scores predicting outcomes showing >96% success for score 0. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

The research aims to create a CT-based scoring system to anticipate outcomes of transcatheter tricuspid valve annuloplasty (TTVA).

February 8, 2026

Computed tomography based analyses for predicting procedural outcomes of transcatheter tricuspid valve annuloplasty

Key Result

In severe TR patients, the 5-component CT-Score predicted TTVA success with >96% TR≤2 at discharge for score 0 vs 22% for scores ≥4 (P<0.001).

Key Points

The research aims to create a CT-based scoring system to anticipate outcomes of transcatheter tricuspid valve annuloplasty (TTVA).
Included patients who underwent TTVA from October 2018 to July 2023 at three centers.
Evaluated CT scans using artificial intelligence for predicting outcomes.
Developed a scoring system based on receiver operator curves and regression analyses.
70% of patients achieved TR grade moderate or less at discharge after TTVA.
Patients with a score of 0 showed over 96% success for TR≤2 at discharge.
Only 22% of patients with scores ≥4 achieved the same outcome (P<0.001).

Structured PICO

Does a computed tomography-based scoring system predict procedural success (TR grade moderate or less at discharge) in patients undergoing transcatheter tricuspid valve annuloplasty?

Population

136 patients with functional tricuspid regurgitation (severe 32%, massive 29%, torrential 43%) undergoing transcatheter tricuspid valve annuloplasty, median age 79.5 years, 72% women.

Intervention

Computed tomography (CT)-based 5-component scoring system to predict procedural outcomes

Outcome

Tricuspid regurgitation (TR) grade moderate or less (≤2) at dischargesurrogate

A novel 5-component CT-based score can effectively predict procedural success (reduction to moderate or less TR) following transcatheter tricuspid valve annuloplasty.

Main Result

Absolute Event Rate: 0% vs 0%

Abstract

Abstract Background Transcatheter tricuspid valve annuloplasty (TTVA) is an established treatment for functional tricuspid regurgitation (TR). The proximity of the right coronary artery to the tricuspid anulus plays a key role in determining anatomical feasibility, but other computed tomography (CT)-based factors influencing procedural success remain poorly understood Objectives The aim of this study was to develop a computed tomography (CT) based score to predict procedural outcomes of TTVA. Methods All patients (n = 136) who underwent TTVA between October 2018 and July 2023 at 3 centers were included. CT scans were evaluated using artificial intelligence. A scoring system was derived using receiver operator curves and regression analyses. The endpoint was TR grade moderate or less at discharge. Results The median age was 79.5 years (Q1-Q3: 76-83 years); 72% of patients were women; and patients presented with severe (32%), massive (29%), and torrential (43%) TR. Five variables (right ventricular dilatation, right atrial dilatation, septo-lateral anulus diameter, distance between inferior vena cava and anulus and septal systolic annular excursion) were identified as best predicting procedural outcome (Table 1). TR at discharge ≤2 was observed in 70% of all patients. In patients with a score of 0 (17%), 96% of the patients had TR≤2 at discharge and only 22% of those with scores ≥4 (P0.001). Conclusions In a patient cohort with predominantly torrential TR, TTVA reduced TR to TR≤2 at discharge in 70% of all patients. The CT-Score is a 5-component score that can predict successful TTVA.

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