Evidence for Triaging HPV-Positive Women Using Viral Load: Data from Two Large Cohort Screening Projects in Different Regions of China

Key Points

• The aim is to evaluate the effectiveness of viral load-based triage for identifying cervical precancer and cancer in HPV-positive women.
• Analyzed data from two large cohort projects in different regions of China.
• Assessed the effectiveness of viral load as a triage method without cytology.
• Evaluated the impact on colposcopy referrals and visit reductions.
• Viral load triage effectively identified cervical precancer and cancer in HPV-positive individuals.
• Single-sample collection reduced the need for multiple visits.
• Higher colposcopy referral rates were noted, particularly in areas with unreliable cytology.