Very restrictive versus standard RBC transfusion strategy in anemic critically ill patients (VeRTEx): Protocol for a pilot randomized controlled trial

Key Points

• The trial aims to compare very restrictive and standard strategies for red blood cell transfusion in critically ill patients with anemia.
• Pilot randomized controlled trial design
• Involving anemic critically ill patients
• Comparison of two transfusion strategies
• Registration with SPIRIT guidelines
• Evaluation of feasibility for larger trials
• Assessment of safety and efficacy of transfusion strategies