Acceleration of the Arbuzov-type reaction via double activation of imine and H -phosphonate

Key Points

• This research aims to explore the synthesis process of pyrrolidine derivatives using an imine and H-phosphonates through acceleration techniques.
• Utilized imine and H-phosphonates in reaction conditions
• Synthetically produced 3-arylidene-1-pyrrolinium trifluoroacetate
• Applied double activation mechanism
• Successful synthesis of pyrrolidine derivatives
• Organophosphorus moiety was integrated at the 2-position
• Demonstrated enhanced reactivity with double activation