What question did this study set out to answer?

The research aims to assess changes in olfactory bulb volume and olfactory function in patients with eosinophilic chronic rhinosinusitis following surgery.

February 11, 2026The Laryngoscope0 citationsOpen Access

View Full Paper

Olfactory Bulb Volume and Function Recovery in Eosinophilic Chronic Rhinosinusitis

KYKeisuke Yamamoto MAMasaki Abukawa TOTsuyoshi Okuni

Key Points

The research aims to assess changes in olfactory bulb volume and olfactory function in patients with eosinophilic chronic rhinosinusitis following surgery.
Retrospective observational study design at a single center
Included 32 patients with eosinophilic chronic rhinosinusitis
Olfactory function assessed pre- and postoperatively using multiple tests
Olfactory bulb volume measured from MRI images with FIESTA
Logistic regression analyzed predictors of OBV change.
Postoperative scores for olfactory function tests improved significantly.
Mean olfactory bulb volume increased by 10.3% postoperatively, not statistically significant (p = 0.095).
OBV change correlated with improvements in olfactory identification (OE and OSIT-J scores).
Longer odor duration and higher SAOQ scores predicted smaller increases in OBV.

Abstract

ABSTRACT Objective To evaluate perioperative changes in olfactory bulb volume (OBV) and olfactory function in patients with eosinophilic chronic rhinosinusitis (ECRS) using 3T magnetic resonance imaging (MRI) with fast imaging employing steady‐state acquisition (FIESTA) sequence and to assess their associations. Methods This single‐center, retrospective observational study included 32 patients with ECRS who underwent functional endoscopic sinus surgery. Olfactory function was assessed pre‐ and postoperatively using the Alinamin test, T OSIT‐J: r = 0.402, p = 0.022), which should be interpreted as exploratory. Multivariate analysis revealed that longer odor duration on the Alinamin test (≥ 50 s) and higher SAOQ scores predicted smaller OBV increases. Conclusion OBV measurement using 3T MRI with FIESTA may provide a structural correlate of olfactory changes in ECRS. The observed correlation between OBV changes and olfactory identification suggests a potential relationship with postoperative functional recovery. Level of Evidence 4.

Perguntar à IA

Bookmark

View Full Paper

Cite This Study

Yamamoto et al. (Sat,) studied this question.

synapsesocial.com/papers/698c1bb8267fb587c655d8f6 https://doi.org/https://doi.org/10.1002/lary.70415

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

Perguntar à IA

Bookmark

View Full Paper