Deciphering the Predictive Utility of N-telopeptide (NTx) and C-telopeptide (CTx) for Early Bony Invasion in Oral Squamous Cell Carcinoma (OSCC)

Key Points

• The aim is to evaluate the utility of NTx and CTx levels as biomarkers for early detection of bony invasion in OSCC.
• Measured serum levels of NTx and CTx in OSCC patients.
• Included CT scan results to assess bony microinvasion.
• Analyzed the correlation between elevated biomarker levels and imaging results.
• Elevated serum NTx and CTx levels were found in OSCC patients with negative CT scans.
• These biomarkers may signal early bony microinvasion before visible imaging changes.
• Incorporating these tests could refine diagnostic protocols and improve treatment outcomes.