New Aspects of Thiomorpholine Chemistry

Key Points

• The review aims to summarize recent advancements in the synthesis and properties of thiomorpholines over the last 10–15 years.
• Analyzed literature data on thiomorpholine chemistry published in the past decade and a half.
• Reviewed new synthesis methods including the formation of thiomorpholine rings.
• Considered reactions involving sulfur dichloride and various amines and S,N-containing compounds.
• Identified new methods for constructing thiomorpholine rings.
• Highlighted the formation of thiomorpholine derivatives from sulfur dichloride with primary and secondary amines.
• Discussed the significance of new S,N-containing initial compounds in thiomorpholine synthesis.