This paper presents a unified, closure-based derivation linking physics, chemistry, and biology through a forced sequence of structural layers: particles, atoms, chemistry, RNA, cells, and DNA. Within the ψ₀-OCM (Osborne Cosmological Model), these layers arise as stable closure states of redistribution dynamics under bounded detachment, rather than as contingent historical or environmental accidents. A single forcing principle determines why each layer must emerge and persist, and why Darwinian natural selection becomes operative only after specific closure thresholds are achieved. Established physical, chemical, and biological theories are recovered as reduction limits on stabilized closure domains, preserving their empirical validity while situating them within a common generative framework. The result is a law-level connective architecture that explains the natural hierarchy of matter and life without undermining the autonomy of existing disciplines.
John Francis Osborne (Mon,) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: