Construction and Application of a Biological Sample Library Information Management System Based on a Data Governance System in China

Objectives: This study aimed to develop and implement a hospital-based Biobank Information Management System (Version 1.0) within a structured data governance framework, and to evaluate its effectiveness in improving standardized biospecimen management, operational efficiency, and research support capacity in real-world clinical settings.Methods: A Biobank Information Management System (Version 1.0) was independently developed and deployed at Foshan Fosun Chancheng Hospital. The system incorporated data governance principles across the entire biospecimen lifecycle, including donor information management, sample collection, processing, storage, retrieval, and utilization. It successfully obtained national software copyright registration and was fully integrated into routine clinical and research workflows.Results: Post-implementation evaluation demonstrated a 67% reduction in manual operational workload, a 4.2-minute decrease in average sample retrieval time, and a data standardization rate of 90%. In addition, the system implemented role-based access control, standardized data dictionaries, audit trails, and full lifecycle traceability, thereby strengthening compliance with regulatory and ethical requirements. Collectively, these quantitative and functional outcomes indicate substantial improvements in workflow efficiency, data consistency, accuracy, and management transparency compared with traditional manual or semi-digital biobank operations.Conclusions: This study demonstrates that embedding data governance principles into the design and construction of a hospital-based biobank information system provides a sustainable, secure, and standardized approach to biospecimen management. The proposed system offers a practical and replicable reference for healthcare institutions seeking to modernize biobank infrastructure and strengthen biomedical research support.