The process of folliculogenesis, during which the ovary develops, is an important step to ensure healthy reproduction. However, it has predominantly been studied in mice, and direct molecular comparisons to human folliculogenesis have remained technically challenging. In a new study, Hiroshi Ohta, Mitinori Saituou and colleagues perform transcriptional analysis to compare human, mouse and monkey ovarian follicles. To find out more, we spoke to first author Baku Nakakita and co-corresponding authors Mitinori Saitou, Professor at the University of Kyoto, Japan, and Hiroshi Ohta, Associate Professor at the University of Kyoto.
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