Radiation-induced Skin Necrosis Following Intra-articular Yttrium-90 Hydroxyapatite in a Patient with Chronic Knee Synovitis

Radionuclide synovectomy using Yttrium-90 hydroxyapatite has been shown to be a safe and effective treatment for patients with chronic synovitis. However, cutaneous radiation necrosis is a rare complication of this procedure. Potential causes include improper radionuclide injection, leakage, or extra-articular deposition. Early recognition of this adverse effect is critical for implementing an appropriate treatment strategy and avoiding unnecessary interventions. This case report presents an instance of radiation-induced skin necrosis following intra-articular administration of Yttrium-90 in a patient with chronic knee synovitis.