A rational development of a drug delivery device based on MOF UiO-66 for calcium channel blockers drugs

Key Points

• To develop an effective drug delivery device for calcium channel blockers using MOF UiO-66.
• Utilized metal-organic framework (MOF) UiO-66 for drug encapsulation.
• Evaluated the solubility and absorption properties of Amlodipine, Nifedipine, and Nimodipine.
• Analyzed the delivery device's performance in releasing drugs effectively.
• Demonstrated enhanced solubility of calcium channel blockers.
• Showed improved absorption rates compared to traditional methods.
• Suggests potential for better therapeutic outcomes in cardiovascular conditions.