Illuminating Microtubular Function With Small Molecules: Past, Present and Future of Fluorescent Tubulin-Binding Probes

Key Points

• The aim is to review the development and application of fluorescent probes for studying microtubules and their functions.
• Analyzed past and current fluorescent probes used for tubulin visualization.
• Discussed the methodologies for real-time observation of microtubule dynamics.
• Evaluated the implications of these probes on understanding cellular processes.
• Fluorescent probes significantly enhance the visualization of microtubules in live cells.
• Advances in probe technology have improved our understanding of microtubule dynamics in cell division and migration.
• Future directions focus on developing more specific and effective tubulin-binding probes.