Chemical Reaction-Enabled Lipidomics: From Sensitive Structural Analysis to Biomedical Applications

Key Points

• The aim is to explore how chemical reactions can enhance lipid analysis and its applications in understanding metabolism and diseases.
• Utilized chemical reactions to improve lipid identification and quantification.
• Analyzed diverse lipid structures with varying ionization efficiencies.
• Applied findings to understand disease pathology and metabolic processes.
• Enhanced structural insights into a wide range of lipid molecules.
• Improved sensitivity in detecting lipids with diverse structural characteristics.
• Established connections between lipid profiles and disease states.