Enantioselective Synthesis of Antibiotic Inducing Gamma-Butenolides from Streptomyces rochei and Derivatives

Key Points

• This research aims to explore the enantioselective synthesis of gamma-butenolides derived from Streptomyces rochei.
• Utilized a divergent synthesis approach
• Investigated regulatory systems in antibiotic production
• Analyzed derivatives of gamma-butenolides
• Successfully synthesized two known gamma-butenolides
• Demonstrated enantioselectivity in synthesis process
• Identified potential pathways for antibiotic production