What question did this study set out to answer?

This research aims to identify the Pegivirus C genome in a febrile outbreak to understand its role in human health.

February 13, 2026Open Access

Detection of Novel Pegivirus C Genome in an Unexplained Febrile Outbreak, Gombe State, Nigeria, 2024 by Enhanced mNGS Approach

Key Points

This research aims to identify the Pegivirus C genome in a febrile outbreak to understand its role in human health.
Enhanced metagenomic next-generation sequencing (mNGS) was employed.
Samples from febrile patients were analyzed for viral genome presence.
The outbreak was monitored for transmission dynamics and clinical implications.
Uniform detection of Pegivirus C genome in outbreak samples.
Potential link between Pegivirus C and febrile illness was observed.
Calls for further investigation into the virus's pathogenicity and transmission were raised.

Abstract

The uniform detection of Pegivirus C in this localized outbreak raises concern over its potential pathogenic or co-pathogenic role. These findings support the need for further investigation into its transmission dynamics, tropism, and clinical relevance.

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Cite This Study

Lawal et al. (Sun,) studied this question.

synapsesocial.com/papers/698ebeb185a1ff6a93015fcc https://doi.org/https://doi.org/10.1016/j.ijid.2026.108470

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