What question did this study set out to answer?

The study examines how diffusion tensor imaging metrics relate to structural and cerebrovascular imaging in idiopathic normal pressure hydrocephalus.

February 13, 2026Open Access

Associations of Diffusion Tensor Imaging Metrics with Structural and Cerebrovascular Disease Imaging Metrics in Idiopathic Normal Pressure Hydrocephalus

Key Points

The study examines how diffusion tensor imaging metrics relate to structural and cerebrovascular imaging in idiopathic normal pressure hydrocephalus.
Utilized diffusion tensor imaging analysis along the perivascular space
Analyzed structural imaging metrics
Investigated cerebrovascular disease-related imaging features
Found significant associations between diffusion tensor imaging metrics and structural imaging metrics
Observed correlations with cerebrovascular disease indicators
Results suggest potential biomarkers for diagnosing idiopathic normal pressure hydrocephalus

Abstract

DTI-ALPS = diffusion tensor imaging analysis along the perivascular space; iNPH = idiopathic normal pressure hydrocephalus; (C)DESH = (computation) disproportionately enlarged subarachnoid space hydrocephalus; PVS = perivascular space; WMH = white matter hyperintensity; FA = fractional anisotropy; GCC = genus of corpus callosum; AUROC = area under the receiver operating characteristic curve.

Associations of Diffusion Tensor Imaging Metrics with Structural and Cerebrovascular Disease Imaging Metrics in Idiopathic Normal Pressure Hydrocephalus

Key Points

Abstract

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