Convergent Synthesis of Highly Functionalized Furans

Key Points

• The research aims to develop a one-pot synthesis method for highly functionalized furans using specific starting materials.
• Utilized two starting materials: 2-methyleneoxetanes and α-diazoketones.
• Applied transition-metal-mediated cyclopropanation followed by rearrangement and elimination.
• Conducted the synthesis as a mild, convergent process to achieve controlled furan functionalization.
• Successfully synthesized various highly functionalized furans.
• Demonstrated the effectiveness of the one-pot approach.
• Controlled the level of furan functionalization through the described methods.