Genetic insights into hepatocellular carcinoma: the role of VDR FokI (rs2228570) and TaqI (rs731236) polymorphisms in Egyptian patients

Key Points

• This research aims to explore the influence of VDR FokI and TaqI polymorphisms on the risk of hepatocellular carcinoma in Egyptians.
• Analysis of genetic variants in the VDR gene.
• Focus on FokI (rs2228570) and TaqI (rs731236) polymorphisms.
• Population-based study among Egyptian patients.
• Individuals with specific VDR polymorphisms show a higher risk for developing hepatocellular carcinoma.
• The findings suggest a genetic predisposition to this cancer type among the Egyptian population.