Effects of gestational perfluorohexanesulfonic acid exposure at human realistic dose on social communication deficit in mouse offspring

Key Points

• This work aims to investigate the effects of gestational exposure to perfluorohexanesulfonic acid on social communication in mouse offspring.
• Conducted a series of behavioral tests to assess social communication in mouse offspring
• Administered human realistic doses of perfluorohexanesulfonic acid during gestation
• Utilized comparative analysis to evaluate results against control groups
• Mouse offspring showed significant deficits in social communication behaviors
• Behavioral changes were directly correlated with levels of gestational exposure to perfluorohexanesulfonic acid
• Statistical analysis revealed a noteworthy difference in communication skills between exposed and unexposed groups