Preclinical evaluation of progesterone combined with EDP-M scheme in 2D and 3D models of adrenocortical carcinoma

Key Points

• The aim is to evaluate the efficacy of progesterone combined with EDP-M against adrenocortical carcinoma.
• Conducted experiments using 2D and 3D models of adrenocortical carcinoma.
• Assessed the cytotoxic effects of progesterone and EDP-M combination.
• Performed evaluations of treatment efficacy in preclinical settings.
• Progesterone significantly improved the cytotoxic effects of the EDP-M scheme.
• Enhanced effectiveness observed in both 2D and 3D models of adrenocortical carcinoma.