To contact or not: an investigation into the polymeric surface interactions with human insulin and their therapeutic implications

Key Points

• This research aims to explore how polymer interactions affect the function of insulin in therapeutic settings.
• Analyzed the interactions between insulin and various polymers in a controlled environment.
• Evaluated the impact of these interactions on insulin's bioavailability.
• Assessed potential agglomeration effects resulting from polymer contact.
• Polymer interactions led to significant agglomeration of insulin, impairing its function.
• Bioavailability of insulin was notably reduced in the presence of certain polymers.

Abstract