Association between autoantibodies and interstitial lung disease in autoimmune disease patients: a retrospective study

Key Points

• To investigate the relationship between autoantibodies and interstitial lung disease (ILD) in patients with autoimmune diseases.
• Retrospective analysis of autoantibody presence in patients with autoimmune diseases.
• Assessment of interstitial lung disease incidence in relation to autoantibody levels.
• Data collection on age and specific autoantibodies, such as anti-Ro52 and anti-MDA5.
• Anti-Ro52 and anti-MDA5 were significant predictors of ILD.
• Younger age was also identified as a contributing factor to ILD presence.
• Findings suggest that autoantibodies may serve as effective biomarkers for early ILD detection.