Aryne-involved α-C(sp3)–H arylation of 4-aminopyrazolones via two distinct systems: dual phase-transfer catalysis and ultraviolet photochemistry

Key Points

• The aim is to develop a method for directly arylating C(sp3)–H bonds in 4-aminopyrazolones using arynes.
• Utilized dual phase-transfer catalysis with triaminocyclopropenium salts.
• Employed ultraviolet photochemistry to facilitate the reaction.
• Investigated arylation efficiency under various conditions.
• Successfully achieved direct C(sp3)–H arylation of 4-aminopyrazolones.
• Demonstrated the effectiveness of dual phase-transfer catalysis in reaction yield.
• Showed significant enhancements in arylation via ultraviolet irradiation.