(E)-Methyl 3-(2-amino-4-chloro-6-morpholinopyrimidin-5-yl)acrylate

Key Points

• To synthesize (E)-methyl 3-(2-amino-4-chloro-6-morpholinopyrimidin-5-yl)acrylate using a specific reaction.
• Utilized a Schlosser-modified Wittig reaction for synthesis.
• Performed 1H and 13C NMR for structure confirmation.
• Confirmed E-alkene formation through complete signal assignments.
• Successfully synthesized target compound (E)-methyl 3-(2-amino-4-chloro-6-morpholinopyrimidin-5-yl)acrylate.
• Achieved complete NMR signal assignments confirming structural integrity.